Systematic review on the relationship between HIV, Antiretroviral Therapy (ART), hyperglycemia and hypercholesteremia

Abstract

HIV (Human Immunodeficiency Virus) infection continues to be a global public health concern, with millions of people living with the virus around the world, largely due to advances in Antiretroviral Therapy (ART) associated with ostensible prevention campaigns. However, if on the one hand a significant increase in the survival of patients with HIV is observed with the use of ART, on the other hand several studies warn of the adverse effects of prolonged use of ART on the metabolic system, particularly in the induction of a persistent hyperglycemic and hypercholesterolemic state, disorders that contribute to the overall reduction in survival due to the emergence of complications related to prolonged hyperglycemia and dyslipidemia, which motivated the present systematic review on the topic.